Bile Acid Sequestrants
Bile acid sequestrants bind with bile acids that contain cholesterol in the intestines and are then eliminated in the stool. They are proven to reduce LDL by 10 to 20%. Small doses produce decent reductions in LDL. They are sometimes prescribed along with a statin to enhance reduction. When combined, their effects are counted together and lower LDL by more than 40%. They do not lower triglycerides.
People who are allergic to bile acid sequestrants should not take this medication nor should anyone who has a medical history of bile obstruction.
There may be interactions with other drugs so make certain your doctor has a complete list of all prescribed and non-prescribed medications you are taking.
Bile acid sequestrants do not become absorbed from the gastrointestinal tract. It has been used for 30+ years and is considered safe for long term use.